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Home / Antibodies

CD36 Antibody (V3002SAF)

SKU : BHA17124601

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NSJ Bioreagents

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Mfr.No.	V3002SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is intealized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. (UniProt)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Stimulated human leukocytes were used as the immunogen for the CD36 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human
Note	This mAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.Optimal dilution of the CD36 antibody should be determined by the researcher.

Uniprot	P16671

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD36 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Functional studies, FACS, IF
Description	Functional studies (order BSA/sodium azide-free format),Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124601	V3002SAF-100UG	100 ug	$499		Add to Cart

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