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Home / Antibodies

CD34 Antibody

SKU : BHA10557540

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA269036
Alternative Names	CD34
Categories	Primary Antibodies
Clonality	polyclonal
Description	Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.Fackler M.J.et.al(1990)Chem. 265:11056-11061
Host	Rabbit
Immunogen	Peptide sequence around aa.377~381(Q-H-V-V-A) derived from Human CD34.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Fackler M.J.et.al(1990)Chem. 265:11056-11061
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total CD34 protein.
Subcellular Location	Membrane, Single-pass type I membrane protein

Uniprot	P28906
Database Links	HGNC:1662 OMIM:142230 KEGG:hsa:947 STRING:9606.ENSP00000310036 UniGene:Hs.374990
Function	Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Pathway	Hematopoietic cell lineage Neurotrophin signaling pathway
Protein Families	CD34 family
Tissue Specificity	Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557540	CSB-PA269036	100ul	$297		Add to Cart

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