The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alteately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A purified His-tagged recombinant protein fragment was used to produced this CD25 antibody.
Isotype
Mouse IgG2a
Species Reactivity
Human
Note
Titration of the CD25 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P01589
Format
Ascites
Purity
Ascites
Storage
Aliquot the CD25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.