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Home / Primary Antibodies

CD22 Antibody (V3784SAF)

SKU : BHA17125609

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NSJ Bioreagents

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Mfr.No.	V3784SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 52-178 from the human protein were used as the immunogen for the CD22 antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the CD22 antibody should be determined by the researcher.

Uniprot	P20273

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD22 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, ELISA, FACS, IF
Description	ELISA: 2-4ug/ml (order BSA/azide-free format),Weste blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125609	V3784SAF-100UG	100 ug	$499		Add to Cart

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