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Home / Primary Antibodies

CD1d Antibody (R30948)

SKU : BHA17104482

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NSJ Bioreagents

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Mfr.No.	R30948
Clonality	Polyclonal
Description	CD1d is the sole group-2 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T (NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production. Jayawardena-Wolf et al. described 2 different pathways of CD1d trafficking to endosomal compartments in mouse cells. A tyrosine-based motif goves recycling between the plasma membrane and the endosome, while CD1d associates, like major histocompatibility complex class II antigens, with the invariant chain, or II, in the endoplasmic reticulum. Both pathways enhance antigen presentation to CD1d-restricted natural killer T cells.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 76-92 (FSDQQWETLQHIFRVYR-human) were used as the immunogen for this CD1d antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P15813

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the CD1d antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104482	R30948	100 ug	$419		Add to Cart

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