Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.Manabu Fujimoto, J. Biol. Chem., Nov 2001; 276: 44820 - 44827. LE Bradbury, J. Immunol., Sep 1993; 151: 2915. Minoru Hasegawa, J. Immunol., Sep 2001; 167: 2469.
Host
Rabbit
Immunogen
Synthesized non-phosphopeptide derived from Human CD19 around the phosphorylation site of tyrosine 531 (D-S-Y(p)-E-N)., Synthesized non-phosphopeptide derived from Human CD19 around the phosphorylation site of tyrosine 531 (D-S-Y(p)-E-N).
Involvement In Disease
Immunodeficiency, common variable, 3 (CVID3), Immunodeficiency, common variable, 3 (CVID3)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Manabu Fujimoto, J. Biol. Chem., Nov 2001; 276: 44820 - 44827. LE Bradbury, J. Immunol., Sep 1993; 151: 2915. Minoru Hasegawa, J. Immunol., Sep 2001; 167: 2469.
Species
Homo Sapiens (Human), Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CD19 protein., The antibody detects endogenous levels of total CD19 protein.
Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation., Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol., Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen., The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen., The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze., Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.