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Home / Antibodies

CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1 (V3226)

SKU : BHA17113617

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NSJ Bioreagents

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Mfr.No.	V3226, V3226-20UG, V3226-100UG
Clonality	Monoclonal
Description	P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cell surface

Uniprot	Q14242
Clone No	PSGL1/1601

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity
Storage	Store the PSGL-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	IHC-P
Dilution	Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17113617-1	V3226-20UG	20ug	$219		Add to Cart
BHA17113617-2	V3226-100UG	100ug	$499		Add to Cart

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