CD151 is involved in a wide variety of cell biological processes, including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein, which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including 1, 3, 4, 3/ 1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Isotype
Mouse IgG1, kappa
Species Reactivity
Human
Note
Optimal dilution of the CD151 antibody should be determined by the researcher.
Uniprot
P48509
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the CD151 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
FACS, IF, WB, IHC-P
Description
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT