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Home / Antibodies

CD146 Antibody / MCAM / MUC18 (V7943SAF)

SKU : BHA17127079

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NSJ Bioreagents

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Mfr.No.	V7943SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 226-374) was used as the immunogen for the MCAM antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P43121

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the MCAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/mcam-antibody-mcam-3046-v7943" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127079	V7943SAF-100UG	100 ug	$499		Add to Cart

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