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Home / Primary Antibodies

CD133 Antibody / PROM1 (Extracellular Region) (V9215)

SKU : BHA17119604

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NSJ Bioreagents

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Mfr.No.	V9215, V9215-20UG, V9215-100UG
Clonality	Monoclonal (mouse origin)
Description	CD133, also known as PROML1 or Prominin, is a stem cell antigen that may be useful for the selection and expansion of hematopoietic cells and may be used as a positive marker for the characterization of trophoblast cell lines. The human CD133 gene maps to chromosome 4p15.32 and encodes an 865 amino acid protein. The CD133 gene codes for a pentaspantransmembrane glycoprotein that is expressed on primitive hematopoietic stem, progenitor, retinoblastoma, hemangioblasts and neural stem cells and developing epithelium. The 5-TM structure includes an extracellular N-terminus, two short intra- cellular loops, two large extracellular loops and an intracellular C-terminus. CD133 is a candidate gene for retinal proteins that are targeted to plasma membrane protrusions. These retinal proteins, including CD133, may influence the shedding of photoreceptive membranes from the terminal end of the outer segments of vertebrate photoreceptors, where they are phagocytosed by the retinal pigment epithelium, and represent candidates for inherited retinal degenerations.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A chimeric protein composed of a portion of amino acids 180-380 and 612-765 (extracelluar regions) was used as the immunogen for the CD133 antibody. This Mab recognizes both glycosylated and non-glycosylated extracellular domains of CD133.
Isotype	Mouse IgG1
Species Reactivity	Human
Note	Optimal dilution of the CD133 antibody should be determined by the researcher.

Uniprot	O43490

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the CD133 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119604-1	V9215-20UG	20ug	$219		Add to Cart
BHA17119604-2	V9215-100UG	100ug	$499		Add to Cart

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