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Home / Primary Antibodies

CD13 Antibody / ANPEP (V2557SAF)

SKU : BHA17123992

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NSJ Bioreagents

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Mfr.No.	V2557SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This mAb recognizes an extracellular epitope of an integral membrane glycoprotein of 150kDa, identified as CD13. This antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. It is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted patte of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant human CD13 was used as the immunogen for the CD13 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the CD13 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min

Uniprot	P15144

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA/sodium azide-free format for coating)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123992	V2557SAF-100UG	100 ug	$499		Add to Cart

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