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Home / Primary Antibodies

CD105 Antibody / Endoglin (V3341)

SKU : BHA17113810

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NSJ Bioreagents

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Mfr.No.	V3341, V3341-20UG, V3341-100UG
Clonality	Monoclonal
Description	CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. It is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	A partial recombinant protein corresponding to amino acids 74-251 of human CD105/Endoglin was used as the immunogen for the Endoglin antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cell surface, cytoplasmic

Uniprot	P17813
Clone No	ENG/1327

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the Endoglin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	WB
Dilution	Weste blot: 1-2ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17113810-1	V3341-20UG	20ug	$219		Add to Cart
BHA17113810-2	V3341-100UG	100ug	$499		Add to Cart

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