Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. (UniProt)
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 272-300 from the human protein was used as the immunogen for this CD10 antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P08473
Format
Ascites
Purity
Ascites
Storage
Aliquot the CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.