The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. (provided by RefSeq).
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P32248
Format
Ascites
Purity
Ascites
Storage
Aliquot the CCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.