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Home / Primary Antibodies / Monoclonal Antibodies

Cav1.2 Antibody, Clone S57 - SMC-300

BHA11902443
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+1 866.986.9598
Email
[email protected]
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Swissprot P15381
Accession Number NP_001129994.1
Gene Id 100101555
Target Cav1.2
Clone No S57
Research Area cardiovascular System, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels, Cancer, Cell Signaling, Heart, Neuroscience
Buffer PBS pH7.4, 50% glycerol, 0.1% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), IHC (1:1000), ICC/IF (1:100), IP (1:200); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart (1). It may be associated with a variant of Long QT syndrome called Timothy's syndrome (2, 3) and also with Brugada syndrome. Some references also suggest it is related to bipolar disease as well (3).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~240kDa (varies with cell background due to glycosylation).
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications AM, IHC, IP, WB, ICC/IF
Description WB ; IHC ; ICC ; IF ; IP ; AM
Dilution WB (1:1000), IHC (1:1000), ICC/IF (1:100), IP (1:200); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Splawski I., et al. (2004) Cell. 119 (1): 19-31.

2. Krey J.F., and Dolmetsch R. (2009) Biophysical. 96 (3): 221a-222a.

3. Crotti L., Celano G., Dagradi F. and Schwartz P.J. (2008) Orphanet J Rare Disease 3:18.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11902443-1 SMC-300D Unconjugated 100 ug $330
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BHA11902443-2 SMC-300D-A390 ATTO 390 100 ug $384
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BHA11902443-3 SMC-300D-A488 ATTO 488 100 ug $383
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BHA11902443-4 SMC-300D-A594 ATTO 594 100 ug $383
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BHA11902443-5 SMC-300D-ALP Alkaline Phosphatase 100 ug $376
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BHA11902443-6 SMC-300D-APC APC 100 ug $382
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BHA11902443-7 SMC-300D-BI Biotin 100 ug $378
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BHA11902443-8 SMC-300D-FITC FITC 100 ug $374
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BHA11902443-9 SMC-300D-HRP HRP 100 ug $370
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BHA11902443-10 SMC-300D-PCP PerCP 100 ug $382
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BHA11902443-11 SMC-300D-RPE RPE 100 ug $380
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BHA11902443-12 SMC-300S Unconjugated 12 ug $44
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