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Home / Antibodies

Cathepsin L Antibody / CTSL (RQ6857)

SKU : BHA17119269

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NSJ Bioreagents

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Mfr.No.	RQ6857
Clonality	Polyclonal (rabbit origin)
Description	The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell.
Host	Rabbit
Immunogen Region	Amino acids EATEESCKYNPKYSVAND from the human protein were used as the immunogen for the CTSL antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse
Recombinant	No

Uniprot	P07711

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the CTSL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 1-2ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119269	RQ6857	100ug	$419		Add to Cart

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