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Home / Antibodies

CAR Antibody Coxsackie Adenovirus Receptor (R30950)

SKU : BHA17104483

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NSJ Bioreagents

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Mfr.No.	R30950
Clonality	Polyclonal
Description	Coxsackie virus and adenovirus receptor is a protein that in humans is encoded by the CXADR gene, also known as CAR, CVB3-binding protein, and Coxsackievirus B-adenovirus receptor. The cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northe blot analysis, the highest expression of 1.4-kb and 6-kb transcripts are in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse CAR showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human Coxsackie Adenovirus Receptor (YSKTQYNQVPSEDFER) was used as the immunogen for this CAR antibody (100% homologous in human, mouse and rat).
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	P78310

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the CAR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104483	R30950	100 ug	$419		Add to Cart

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