The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.Qin N., Mol. Pharmacol. 62:485-496(2002).Bechtel S., BMC Genomics 8:399-399(2007).Scherer S.E., Nature 440:346-351(2006)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CACNA2D4.
Involvement In Disease
Retinal cone dystrophy 4 (RCD4)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.
Pathway
MAPK signaling pathway Cardiac muscle contraction
Protein Families
Calcium channel subunit alpha-2/delta family
Tissue Specificity
Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pi
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.