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Home / Primary Antibodies

C1QB Antibody / Complement C1q B-Chain (V8815)

SKU : BHA17119363

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NSJ Bioreagents

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Mfr.No.	V8815, V8815-20UG, V8815-100UG
Clonality	Monoclonal (mouse origin)
Description	C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 41-188 was used as the immunogen for the Complement C1q B-Chain antibody.
Isotype	Mouse IgG, kappa
Species Reactivity	Human
Note	Optimal dilution of the Complement C1q B-Chain antibody should be determined by the researcher.

Uniprot	P02746

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the Complement C1q B-Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119363-1	V8815-20UG	20ug	$219		Add to Cart
BHA17119363-2	V8815-100UG	100ug	$499		Add to Cart

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