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Home / Antibodies

C1QA Antibody / Complement C1q A-Chain (V8057SAF)

SKU : BHA17127182

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NSJ Bioreagents

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Mfr.No.	V8057SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 104-237) was used as the immunogen for the C1QA antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P02745

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the C1QA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA, WB
Description	ELISA (order BSA-free format for coating),Weste blot: 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/c1qa-antibody-c1qa-2783-v8057" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127182	V8057SAF-100UG	100 ug	$499		Add to Cart

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