The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Clonality
Polyclonal
Description
Rabbit Anti-c-Fos Polyclonal Antibody
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, Liquid solution
Host
Rabbit
Immunogen
Synthesized peptide derived from human c-Fos around the non-phosphorylation site of S374
Immunogen Region
Synthesized peptide derived from human c-Fos around the non-phosphorylation site of S374
Isotype
Rabbit IgG
Molecular Weight
58 KD
Others
c-Fos Polyclonal Antibody detects endogenous levels of c-Fos protein.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity
Human, Mouse, Rat
Tag
Proto-oncogene c-Fos
Note
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:200), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Accession Number
P01100
Gene Id
2353, 2353
Concentration
1 mg/ml, 1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.