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Home / Primary Antibodies

c-Abl Antibody / ABL1 (R31857)

SKU : BHA17105211

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NSJ Bioreagents

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Mfr.No.	R31857
Antigen	c-Abl
Clonality	Polyclonal
Description	c-Abl is also called as ABL1. This gene is a proto-oncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene. Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids ERIASGAITKGVVLDSTEALCLAISRNSEQ of human ABL1 were used as the immunogen for the c-Abl antibody.
Isotype	IgG
Predicted Reactivity	Human, Rat
Reactivity	Human, Rat
Recombinant	No

Uniprot	P00519

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the c-Abl antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.1-0.5ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105211	R31857	100 ug	$419		Add to Cart

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