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Home / Antibodies

c-Abl Antibody (ABL1) (F50695)

SKU : BHA17101789

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NSJ Bioreagents

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Mfr.No.	F50695, F50695-0.08ML, F50695-0.4ML
Antigen	ABL1
Clonality	Polyclonal
Description	The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 231-260 from the human protein was used as the immunogen for this ABL1 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P00519

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the ABL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Western blot: 1:1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101789-1	F50695-0.08ML	0.08ml	$165		Add to Cart
BHA17101789-2	F50695-0.4ML	0.4ml	$379		Add to Cart

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