The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Titration of the BTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
Q06187
Format
Ascites
Purity
Ascites
Storage
Aliquot the BTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.