The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.
Isotype
IgG1
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
Q06187
Clone No
488CT2.1.2
Format
Ascites
Purification
Ascites
Storage
Aliquot the BTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.