BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 1313-1342 from the human protein was used as the immunogen for this BRD4 antibody.
Isotype
Rabbit Ig
Species Reactivity
Human
Note
Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
O60885
Format
Purified
Purity
Purified
Storage
Aliquot the BRD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.