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Home / Antibodies

BMPR2 Antibody (F53750)

SKU : BHA17119852

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Mfr.No.	F53750-0.4ML
Clonality	Polyclonal (rabbit origin)
Description	BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 27-56 from the human protein was used as the immunogen for this BMPR2 antibody.
Isotype	Rabbit Ig
Species Reactivity	Human, Mouse
Note	Titration of the BMPR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q13873

Format	Purified
Purity	Purified
Storage	Aliquot the BMPR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC, FACS, ELISA
Description	IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119852	F53750-0.4ML	0.4 ml	$379		Add to Cart

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