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Home / Primary Antibodies / IHC Antibodies

Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1]

SKU : BHA10327455

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1199B
Background	IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-kB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Categories	Primary Antibodies;Primary Antibodies///Flow Cytomerty(FACS)
Clonality	Monoclonal
Host	Rat
Isotype	Rat IgG1, k
Reactivity	Mouse
Synonyms	Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8

Swissprot	Q62386
Accession Number	16171
Gene Id	16171
Clone No	TC11-18H10.1

Buffer	PBS with 0.05% Proclin300, 1% BSA
Concentration	0.5 mg/mL
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	ICFCM

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327455	E-AB-F1199B	50ug	$90		Add to Cart
BHA10327455	E-AB-F1199B	100ug	$140		Add to Cart

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