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Home / Primary Antibodies / Monoclonal Antibodies

Beta-Catenin

SKU : BHA15100403

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Mfr.No.	ARA17-5R
Clonality	Polyclonal
Description	Beta-catenin is a key regulatory protein involved in cell adhesion and signal transduction through the Wnt pathway, and plays important roles in development, cellular proliferation, and differentiation. Mutations of this gene are commonly found in a variety of cancers such as primary hepatocellular carcinoma, colorectal cancer, ovarian carcinoma, breast cancer, lung cancer and glioblastoma. Mutations in the Beta-catenin gene, CTNNB1 leading to stabilization of Beta-catenin in the cytoplasm and translocation to the nucleus have been implicated in various forms of tumor including familial adenomatous polyposis, fibromatosis, solitary fibrous tumors and endometrial carcinoma. A nuclear accumulation of Beta-catenin in fibromatosis (desmoid tumor) in various locations including breast and mesentery is useful in the differentiation of this tumor from other fibroblast like lesions.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	Polyclonal
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
ARA17-5R	ARA17-5R	6 mL	$339		Add to Cart
ARA17-10R	ARA17-10R	100 tests - i6000	$582		Add to Cart
AWA17-50D	AWA17-50D	50 tests - Xmatrx	$356		Add to Cart
AWA17-YCD	AWA17-YCD	160 tests - Xmatrx	$871		Add to Cart

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