Rabbit Anti-Human beta Catenin (pThr41 + pSer45) Polyclonal

Mfr.No.	SPC-1356, SPC-1356D, SPC-1356D-A390, SPC-1356D-A488, SPC-1356D-A594, SPC-1356D-BI, SPC-1356D-FITC
Immunogen Species	Human
Alternative Names	Beta-catenin Antibody, CTNNB Antibody, OK/SW-cl.35 Antibody, PRO2286 Antibody, CTNNB1 Antibody, Catenin beta-1 Antibody
Categories	Antibodies
Cellular Localization	Cytoskeleton, Nucleus, Centrosome, Spindle Pole, Plasma Membrane, Cell Membrane, Cytoplasm, Adherens Junction, Cell Junction, Synapse, Cytosol, Extracellular Exosome, beta-Catenin-Tcf Complex
Clonality	Polyclonal
Description	Rabbit Anti-Human beta Catenin (pThr41 + pSer45) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic phospho-peptide from human beta Catenin around the phosphorylation sites of threonine 41 (pThr41) and serine 45 (pSer45)., Homo Sapiens (Human)
Immunogen Region	Synthetic phospho-peptide from human beta Catenin around the phosphorylation sites of threonine 41 (pThr41) and serine 45 (pSer45).
Isotype	IgG
Launch Date	2018/03/07
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level).

Swissprot	P35222
Gene Id	1499
Target	beta Catenin (pThr41 + pSer45)
Research Area	Cell adhesion, Cell Signaling, Cadherins, Microfilaments, Actin, Neurogenesis, Stem Cells, Signaling Pathways, Wnt / Beta Catenin Pathway, Cancer, Invasion/microenvironment, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Leukocyte Recruitment, Catenins, Neuroscience, Cytoskeleton

Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Dilutions	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level).
Scientific Background	Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects endogenous levels of beta Catenin only when phosphorylated at threonine 41 (pThr41) and serine 45 (pSer45). Detects a band at ~92 kDa.
Storage	-20ºC
Storage Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB
Description	WB
Dilution	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11918594-1	SPC-1356D	Unconjugated	100 ul	$331	Add to Cart
BHA11918594-2	SPC-1356D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11918594-3	SPC-1356D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11918594-4	SPC-1356D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11918594-5	SPC-1356D-BI	Biotin	100 ul	$380	Add to Cart
BHA11918594-6	SPC-1356D-FITC	FITC	100 ul	$375	Add to Cart

beta Catenin Antibody (pThr41 + pSer45) - SPC-1356