Rabbit Anti-Human Beclin 2 Polyclonal

Mfr.No.	SPC-602, SPC-602D, SPC-602D-A390, SPC-602D-A488, SPC-602D-A594, SPC-602D-ALP, SPC-602D-APC, SPC-602D-BI, SPC-602D-FITC, SPC-602D-HRP, SPC-602D-PCP, SPC-602D-RPE, SPC-602S
Immunogen Species	Human
Alternative Names	BECN2 Antibody, Beclin-2 Antibody, Beclin-1 like protein 1 Antibody
Categories	Antibodies
Cellular Localization	Cytoplasm
Certificate Of Analysis	A 1:1000 dilution of SPC-602 was sufficient for detection of Beclin2 on rat liver lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human Beclin 2 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide from the mid-protein of human Beclin 2, Homo Sapiens (Human)
Immunogen Region	Synthetic peptide from the mid-protein of human Beclin 2
Launch Date	2015/10/01
Net Weight (g)	0.1
Reactivity	Rat, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Rat, Human

Swissprot	A8MW95
Accession Number	NP_001277622.1
Gene Id	441925
Target	Beclin 2
Research Area	Cell Signaling, Epigenetics and Nuclear Signaling, Transcription, Cancer, Tumor suppressors, Autophagy, Cancer Metabolism

Buffer	PBS, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	Beclin 2 is a novel coiled-coil protein related to the autophagic Beclin 1 protein. It is thought to interact with Bcl-2, an anti-apoptotic protein, and is believed to function in autophagy. It has alson been found to mediate G protein-coupled receptro (GPCR) degradation (1).
Shipping Temperature	Blue Ice or 4°C
Specificity	Predicted molecular weight at ~48.1kDa. Observed bands in the 50-55kDa range, varied by lysates.
Storage	-20ºC
Storage Buffer	PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB, ICC/IF
Description	WB ; ICC ; IF
Dilution	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. He C., et al. (2013) Cell. 154(5): 1085-1099.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11908033-1	SPC-602D	Unconjugated	100 ug	$331	Add to Cart
BHA11908033-2	SPC-602D-A390	ATTO 390	100 ug	$385	Add to Cart
BHA11908033-3	SPC-602D-A488	ATTO 488	100 ug	$384	Add to Cart
BHA11908033-4	SPC-602D-A594	ATTO 594	100 ug	$384	Add to Cart
BHA11908033-5	SPC-602D-ALP	Alkaline Phosphatase	100 ug	$377	Add to Cart
BHA11908033-6	SPC-602D-APC	APC	100 ug	$383	Add to Cart
BHA11908033-7	SPC-602D-BI	Biotin	100 ug	$380	Add to Cart
BHA11908033-8	SPC-602D-FITC	FITC	100 ug	$375	Add to Cart
BHA11908033-9	SPC-602D-HRP	HRP	100 ug	$371	Add to Cart
BHA11908033-10	SPC-602D-PCP	PerCP	100 ug	$383	Add to Cart
BHA11908033-11	SPC-602D-RPE	RPE	100 ug	$381	Add to Cart
BHA11908033-12	SPC-602S	Unconjugated	12 ug	$44	Add to Cart

Beclin 2 Antibody - SPC-602