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Home / Antibodies

Bcl-2 Antibody (V8837SAF)

SKU : BHA17122892

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NSJ Bioreagents

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Mfr.No.	V8837SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 41-54 (GAAPAPGIFSSQPG) from the human protein were used as the immunogen for the Bcl-2 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the Bcl-2 antibody should be determined by the researcher.

Uniprot	P10415

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the Bcl-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122892	V8837SAF-100UG	100ug	$499		Add to Cart

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