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Home / Antibodies

BCKDK Antibody

SKU : BHA10559239

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA182563
Alternative Names	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase; mitochondrial [Precursor]; EC 2.7.11.4; Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDHKIN
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex By similarity.Chuang J.C., Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human BCKD.
Involvement In Disease	Branched-chain ketoacid dehydrogenase kinase deficiency (BCKDKD)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex By similarity. Chuang J.C., Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total BCKD protein.
Subcellular Location	Mitochondrion matrix, Mitochondrion

Uniprot	O14874
Database Links	HGNC:16902 OMIM:614901 KEGG:hsa:10295 STRING:9606.ENSP00000219794 UniGene:Hs.513520
Function	Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
Protein Families	PDK/BCKDK protein kinase family
Tissue Specificity	Ubiquitous.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559239	CSB-PA182563	100ul	$297		Add to Cart

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