Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.Bardoni A., FEBS Lett. 451:75-80(1999).Liu Y., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 434:724-731(2005).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human B3GALT1.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Bardoni A., FEBS Lett. 451:75-80(1999). Liu Y., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 434:724-731(2005).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total B3GALT1 protein.
Subcellular Location
Golgi apparatus membrane, Single-pass type II membrane protein
Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Protein Families
Glycosyltransferase 31 family
Tissue Specificity
Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.