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Home / Primary Antibodies

AZI2 Antibody

SKU : BHA10558028

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA596738
Alternative Names	5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP; AZI2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.Fujita F., Mol. Cell. Biol. 23:7780-7793(2003).Ota T., Nat. Genet. 36:40-45(2004).Sasai M., J. Immunol. 174:27-30(2005).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human AZI2.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. Fujita F., Mol. Cell. Biol. 23:7780-7793(2003). Ota T., Nat. Genet. 36:40-45(2004). Sasai M., J. Immunol. 174:27-30(2005).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total AZI2 protein.
Subcellular Location	Cytoplasm

Uniprot	Q9H6S1
Gene Id	64343
Database Links	HGNC:24002 OMIM:609916 KEGG:hsa:64343 STRING:9606.ENSP00000419371 UniGene:Hs.706676
Function	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
Tissue Specificity	Widely expressed. Abundant expression seen in the pancreas and testis.
Weight	26,921 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558028	CSB-PA596738	100ul	$297		Add to Cart

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