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Home / Antibodies

Aurora B Antibody / AURKB (V7522IHC)

SKU : BHA17126630

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NSJ Bioreagents

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Mfr.No.	V7522IHC-7ML
Clonality	Recombinant Rabbit Monoclonal
Description	Recognizes a protein of 39kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Rabbit
Immunogen Region	A portion of amino acids 89-251 was used as the immunogen for this recombinant Aurora B antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Optimal dilution of the recombinant Aurora B antibody should be determined by the researcher.

Uniprot	Q96GD4

Format	Purified
Purity	Protein A affinity
Storage	Store the recombinant Aurora B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/recombinant-aurora-b-antibody-aurkb-3121R-v7522" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126630	V7522IHC-7ML	7 ml	$499		Add to Cart

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