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Home / Primary Antibodies

Aurora B Antibody / AURKB (V3241SAF)

SKU : BHA17124903

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NSJ Bioreagents

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Mfr.No.	V3241SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a protein of 39-45kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 89-251 were used as the immunogen for this Aurora B antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the Aurora B antibody should be determined by the researcher.

Uniprot	Q96GD4

Format	Purified
Purity	Protein G affinity
Storage	Store the Aurora B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB
Description	Weste blot: 0.5-1ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124903	V3241SAF-100UG	100 ug	$499		Add to Cart

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