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Home / Antibodies

ATR Antibody / Ataxia telangiectasia and Rad3-related protein / FRP1 (RQ6824)

SKU : BHA17119237

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NSJ Bioreagents

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Mfr.No.	RQ6824
Cellular Localization	Nuclear
Clonality	Polyclonal (rabbit origin)
Description	Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids E730-A1303) was used as the immunogen for the FRP-1 antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Uniprot	Q13535

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the FRP-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, FACS, Direct ELISA
Dilution	Weste blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119237	RQ6824	100ug	$419		Add to Cart

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