This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-3 subunit is not known.Malik N., J. Biol. Chem. 271:22754-22758(1996).Malik N., Mamm. Genome 9:136-143(1998).Zhang H., Nat. Biotechnol. 21:660-666(2003).
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human ATP1B3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-3 subunit is not known.
Malik N., J. Biol. Chem. 271:22754-22758(1996). Malik N., Mamm. Genome 9:136-143(1998). Zhang H., Nat. Biotechnol. 21:660-666(2003).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ATP1B3 protein.
Subcellular Location
Cell membrane, Single-pass type II membrane protein, Melanosome
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.