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Home / Antibodies

ATG5 Antibody (F46220)

SKU : BHA17100934

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NSJ Bioreagents

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Mfr.No.	F46220, F46220-0.08ML, F46220-0.4ML
Clonality	Polyclonal
Description	Macroautophagy is the major inducible pathway for the general tuover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This ATG-5 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the full length of human ATG5.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q9H1Y0

Format	Purified
Purification	Purified
Storage	Aliquot the ATG-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, IF, ELISA
Dilution	Weste blot: 1:500,Immunofluorescence: 1:200,IHC (Paraffin): 1:10-1:50

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17100934-1	F46220-0.08ML	0.08ml	$165		Add to Cart
BHA17100934-2	F46220-0.4ML	0.4ml	$379		Add to Cart

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