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Home / Primary Antibodies

Aryl hydrocarbon Receptor Antibody (AHR) (R30876)

SKU : BHA17104417

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NSJ Bioreagents

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Mfr.No.	R30876
Clonality	Polyclonal
Description	Aryl hydrocarbon receptor, also called AHR and bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. It is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr-/- or Er-alpha -/- ovariectomized mice. CD4-positive cells from mice lacking the recepter developed Th17 responses but failed to produce IL-22 and did not show enhanced Th17 development. Activation of Aryl hydrocarbon receptor during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 832-848 (HPSEARPFPDLTSSGFL-human) were used as the immunogen for this Aryl hydrocarbon Receptor antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P35869

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Aryl hydrocarbon Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104417	R30876	100 ug	$419		Add to Cart

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