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Home / Primary Antibodies

ARNT Antibody

SKU : BHA10557833

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA174700
Alternative Names	Aryl hydrocarbon receptor nuclear translocator; Dioxin receptor; nuclear translocator; HIF-1 beta; Hypoxia-inducible factor 1 beta
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.Hoffman E.C., Science 252:954-958(1991).Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995).Nguyen T.A., Arch. Biochem. Biophys. 367:250-257(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ARNT.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. Hoffman E.C., Science 252:954-958(1991). Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995). Nguyen T.A., Arch. Biochem. Biophys. 367:250-257(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ARNT protein.
Subcellular Location	Nucleus

Uniprot	P27540
Gene Id	405
Database Links	HGNC:700 OMIM:126110 KEGG:hsa:405 STRING:9606.ENSP00000351407 UniGene:Hs.632446
Function	Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Pathway	HIF-1 signaling pathway
Weight	86,366 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557833	CSB-PA174700	100ul	$297		Add to Cart

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