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Home / Primary Antibodies

ARHGEF5 Antibody

SKU : BHA10558649

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA124670
Alternative Names	ARH5; guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor 5
Categories	Primary Antibodies
Clonality	polyclonal
Description	Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.Chan A.M.-L., Oncogene 9:1057-1063(1994).Jikuya H., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ARHGEF5.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. Chan A.M.-L., Oncogene 9:1057-1063(1994). Jikuya H., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 424:157-164(2003)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ARHGEF5 protein.
Subcellular Location	Cytoplasm, Nucleus, Cell projection, podosome

Uniprot	Q12774
Gene Id	7984
Database Links	HGNC:13209 OMIM:600888 KEGG:hsa:7984 STRING:9606.ENSP00000056217 UniGene:Hs.334
Function	Guanine nucleotide exchange factor which activates Rho GTPases
Tissue Specificity	Ubiquitously expressed with highest levels in placenta. High levels are also found in colon, kidney, trachea, prostate, liver, pancreas, pituitary gland, thyroid gland and mammary gland. In fetal tissues, expressed at high levels in kidney, lung and liver
Weight	176799

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558649	CSB-PA124670	100ul	$297		Add to Cart

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