GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.Monaco L., Proc. Natl. Acad. Sci. U.S.A. 87:2206-2210(1990).Kahn R.A., J. Biol. Chem. 266:2606-2614(1991).Lebeda R.A., Gene 237:209-214(1999).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ARF4.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Monaco L., Proc. Natl. Acad. Sci. U.S.A. 87:2206-2210(1990). Kahn R.A., J. Biol. Chem. 266:2606-2614(1991). Lebeda R.A., Gene 237:209-214(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ARF4 protein.
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Protein Families
Small GTPase superfamily, Arf family
Weight
20,511 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.