Rabbit Anti-Human ARAF Polyclonal

Mfr.No.	SPC-1104, SPC-1104D, SPC-1104D-A390, SPC-1104D-A488, SPC-1104D-A594, SPC-1104D-BI, SPC-1104D-FITC
Immunogen Species	Human
Alternative Names	A raf 1 antibody, A Raf proto oncogene serine/threonine protein kinase antibody, ARAF 1 antibody, Araf antibody, ARaf proto oncogene serine/threonine protein kinase antibody, ARAF_HUMAN antibody, ARAF1 antibody, PKS 2 antibody, PKS antibody, PKS2 antibody, RAFA 1 antibody, RAFA1 antibody, Ras binding protein DA Raf antibody, Serine/threonine-protein kinase A-Raf antibody, v raf murine sarcoma 3611 viral oncogene homolog antibody
Categories	Antibodies
Cellular Localization	Cytosol
Certificate Of Analysis	A 1:250 dilution of SPC-1104 was sufficient for detection of ARAF in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human ARAF Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide of human ARaf (AA67-81), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide of human ARaf (AA67-81)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Predominantly in urogenital tissues.

Swissprot	P10398
Accession Number	NP_001645
Gene Id	369
Target	ARAF
Research Area	Neurotransmission, Neurotransmitter Receptors, Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, MAPK Pathway, G Protein Signaling, Small G Proteins, Ras Family, Cancer, Tumor Biomarkers, Oncoproteins, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Predominantly in urogenital tissues.
Scientific Background	ARAF is a tyrosine kinase-like kinase of the Raf family. It is involved in the transduction of mitogenic signals from the cell membrane receptors via Ras and MEK1/2 to the nucleus. It has been implicated in playing a role in the postsynaptic responses of hippocampal neuron. It is inhibited by Nexavar/Sorafenib (IC50>50 nM).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 68 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11914688-1	SPC-1104D	Unconjugated	100 ul	$331	Add to Cart
BHA11914688-2	SPC-1104D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11914688-3	SPC-1104D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11914688-4	SPC-1104D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11914688-5	SPC-1104D-BI	Biotin	100 ul	$380	Add to Cart
BHA11914688-6	SPC-1104D-FITC	FITC	100 ul	$375	Add to Cart

ARAF Antibody - SPC-1104