aryl hydrocarbon receptor-associated protein-9 (ARA9), also known as AIP or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. ARA9/AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that ARA9 is the cellular negative regulator of the hepatitis B virus (HBV) X protein. Mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 91-330) was used as the immunogen for this ARA9 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Gene Id
9049
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the ARA9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
WB, IF, ICC, FACS
Dilution
Western blot: 0.5-1ug/ml,Immunofluorescence: 2-4ug/ml,Flow cytometry: 1-3ug/million cells