Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.Preston G.M., Proc. Natl. Acad. Sci. U.S.A. 88:11110-11114(1991).Moon C., J. Biol. Chem. 268:15772-15778(1993).Ruiz A.C., Biochim. Biophys. Acta 1282:174-178(1996)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human AQP1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Preston G.M., Proc. Natl. Acad. Sci. U.S.A. 88:11110-11114(1991). Moon C., J. Biol. Chem. 268:15772-15778(1993). Ruiz A.C., Biochim. Biophys. Acta 1282:174-178(1996)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total AQP1 protein.
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Protein Families
MIP/aquaporin (TC 1.A.8) family
Tissue Specificity
Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
Weight
16,677 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.