May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.Duchateau P.N., J. Biol. Chem. 272:25576-25582(1997).Duchateau P.N., J. Lipid Res. 42:620-630(2001).Page N.M., Genomics 74:71-78(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human APOL1.
Involvement In Disease
Focal segmental glomerulosclerosis 4 (FSGS4)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Duchateau P.N., J. Biol. Chem. 272:25576-25582(1997). Duchateau P.N., J. Lipid Res. 42:620-630(2001). Page N.M., Genomics 74:71-78(2001).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total APOL1 protein.
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Protein Families
Apolipoprotein L family
Tissue Specificity
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
Weight
44
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.