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Home / Primary Antibodies

APLP2 (Ab-755) Antibody

SKU : BHA10557694

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA546934
Alternative Names	Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.Sprecher C.A., Biochemistry 32:4481-4486(1993).Wasco W., Nat. Genet. 5:95-99(1993).von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y).
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity. Sprecher C.A., Biochemistry 32:4481-4486(1993). Wasco W., Nat. Genet. 5:95-99(1993). von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total APLP2 protein.
Subcellular Location	Cell membrane, Single-pass type I membrane protein, Nucleus

Uniprot	Q06481
Gene Id	334
Database Links	HGNC:598 OMIM:104776 KEGG:hsa:334 STRING:9606.ENSP00000263574 UniGene:Hs.370247
Function	May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
Protein Families	APP family
Tissue Specificity	Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Weight	86,956 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557694	CSB-PA546934	100ul	$297		Add to Cart

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