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Home / Antibodies

ANXA1 (Ab-21) Antibody

SKU : BHA10559150

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA906175
Alternative Names	annexin A1; Annexin I; ANX1; Calpactin II; Chromobindin 9
Categories	Primary Antibodies
Clonality	polyclonal
Description	Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.Wallner B.P., Nature 320:77-81(1986).Kovacic R.T., Biochemistry 30:9015-9021(1991).Arcone R., Eur. J. Biochem. 211:347-355(1993)
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human ANXA1 around the phosphorylation site of tyrosine 21 (Q-E-Y(p)-V-Q).
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Wallner B.P., Nature 320:77-81(1986). Kovacic R.T., Biochemistry 30:9015-9021(1991). Arcone R., Eur. J. Biochem. 211:347-355(1993)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ANXA1 protein.
Subcellular Location	Nucleus, Cytoplasm, Cell projection, cilium, Cell membrane, Membrane, Peripheral membrane protein, Endosome membrane, Peripheral membrane protein, Basolateral cell membrane, Apical cell membrane, Lateral cell membrane, Secreted, Secreted, extracellular space, Cell membrane, Peripheral membrane protein, Extracellular side, Secreted, exosome, Cytoplasmic vesicle, secretory vesicle lumen, Cell projection, phagocytic cup, Early endosome, Cytoplasmic vesicle membrane, Peripheral membrane protein

Uniprot	P04083
Gene Id	301
Database Links	HGNC:533 OMIM:151690 KEGG:hsa:301 STRING:9606.ENSP00000257497 UniGene:Hs.494173
Function	Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity
Protein Families	Annexin family
Tissue Specificity	Detected in resting neutrophils (PubMed:10772777). Detected in peripheral blood T-cells (PubMed:17008549). Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors (PubMed:256648
Weight	38,714 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559150	CSB-PA906175	100ul	$297		Add to Cart

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